Skin Cancer Risk Reduced With Daily Oral Nicotinamide

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Skin Cancer Risk Reduced With Daily Oral Nicotinamide

As the saying goes, “You are what you eat” and hence, if there is a simple supplement that has no significant side effects and prevents skin cancer, then this is a major practical addition to our skin health regimens. Nicotinamide, also known as Niacinamide is a water-soluble form of Vitamin B3 that has been found naturally in meat, fish, nuts, grains & legumes, and is a key component of the glycolysis pathway, by generating Nicotinamide adenine dinucleotide (NAD) for adenosine triphosphate (ATP) production. It has been known to have beneficial anti-inflammatory effects improving acne, rosacea, melasma and some blistering disorders. 

In a landmark study published by The New England Journal of Medicine 2015: 373:1618-26, the authors showed convincingly that over a 12 month period taking Nicotinamide, 386 study patients experienced a 23% reduction in developing nonmelanoma skin cancers (basal cell carcinomas and squamous cell carcinomas) and actinic keratoses (pre-skin cancers) versus those on placebo. The study participants took 500mg twice daily and there did not appear to be any adverse side-effects. However, it is not recommended for those with chronic kidney disease nor those who are pregnant. 

Nicotinamide should not be confused with Niacin, sometimes recommended for lower cholesterol which has been associated with flushing, headaches and elevation of liver enzymes. 

This skin cancer-reducing supplement is not an oral sunscreen and does not replace other sun protection guidance (sunscreens with an SPF of over 40, protective clothing, hats, yearly skin exams and avoiding the hot, mid-day sun.) These are all the mainstays to protect yourself from the sun and skin cancers. Given the safety profile of Nicotinamide, and its protective effects and positive feedback from our patients, I wholeheartedly recommend since it can significantly reduce the incidence of both actinic keratoses and nonmelanoma skin cancers.

Steven L. Greene MD, Advanced Dermatology and Laser Institute of Seattle. Next Page »

The Benefits of a Chemical Peel

A young woman in a white tank top purses her lips and looks off camera

Think of it as gently peeling away the signs of aging. Chemical peel treatment at Advanced Dermatology and Laser Institute of Seattle can beautifully improve the tone, texture, and overall health of your skin with a convenient, in-office treatment.
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What are Dermal Fillers?

Woman receiving dermal filler injections
Dermal fillers can address numerous facial cosmetic issues from wrinkles to fine lines to loss of volume. They can help restore a youthful, vigorous appearance to your face and improve the health of your skin.

At Advanced Dermatology and Laser Institute of Seattle, Dr. Steven Greene has more than 25 years of experience helping his patients revitalize their appearance. He and his team continually educate themselves on the latest dermatological treatments and techniques so they can give you the best possible results. Read on to learn more about what dermal fillers are, how they work, and the dermal filler options that Dr. Greene and his team offer.

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The Future of Cosmetic Consultations

Before beginning cosmetic skincare treatment (i.e. chemical peels, laser skin resurfacing), the most important appointment to schedule with your dermatologist is a consultation. The consultation allows both you and your doctor to discuss any skin-related concerns, prioritize these concerns, and finally–formulate an effective treatment plan to resolve your concerns. Before your consultation begins, ask yourself, “What are my long-term goals regarding skincare?”

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Ask the Expert: Can You Get Skin Cancer “Where the Sun Doesn’t Shine?” Should You Remove All Clothing for a Skin Exam?

Yes, and yes again! While skin cancers are less commonly diagnosed in areas that are normally shielded from the sun, they can and do develop there. There are a number of factors that play a role in the development of skin cancer — including genetics and environmental pollution — that have nothing to do with the sun’s rays. One of the reasons why a complete skin exam is so valuable is that your dermatologist will be able to notice changes that may be normally hidden under clothing. This way, any suspected skin cancers can be diagnosed and treated promptly. Don’t worry, your doctor will respect your modesty with an exam gown and/or cloth draping. Next Page »

Your Guide to PRP: A Nonsurgical Hair Loss Solution

Man with hair lossDid you know that the average person loses around 100 hairs from their scalp in a single day? Healthy hair grows in cycles and it’s completely natural to lose a few strands. But when the natural cycle is disrupted, it can lead to embarrassing hair thinning or hair loss. Thankfully, there is an exciting new treatment called Platelet-Rich Plasma (or PRP) that can effectively stimulate new hair growth.
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Get Rid of That Double Chin with Kybella®!


The double chin can be a real confidence killer. It can leave you feeling embarrassed and ashamed, causing you to shy away from photos and cover it up with certain outfits. But you don’t have to these negative effects any longer. With Kybella®, you can safely and effectively reduce the appearance of the double chin without the need for surgery. Here we’ll dive into the most frequently asked questions Dr. Greene gets about this remarkable treatment. More »

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This Just In: Dr. Greene has Achieved Top Doctor Status on RealSelf!



Over the past several years, RealSelf has become a popular online community for those interested in learning more about plastic surgery and other cosmetic treatments. It’s a vast network of resources like before and after photos, forums where you can ask and answer questions, and information about different procedures, techniques, and qualified providers in your area. This year, we are so happy to announce that our very own Dr. Steven Greene has joined the exclusive Top Doctor club on RealSelf.com! More »

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Seasonal Skin Update

A change in seasons also calls for a change in your skincare routine! It’s that time of year to reorganize your cosmetics drawer with products that combat the harsher fall and soon-to-be winter weather. From barrier creams to bath oils, Dr. Steven Greene gives his professional input on effective treatment regimens for the seasonal skin sufferer.

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